Kim, Keun-Tae Gemechu, Duguma T. Seo, Eunyoung Lee, Taehoon Park, Jong Woong Youn, Inchan Kang, Jong Woo Lee, Song Joo 2024-01-19T09:01:45Z 2024-01-19T09:01:45Z 2023-09-07 2023-08 1932-6203 https://pubs.kist.re.kr/handle/201004/113398 Early detection of venous congestion (VC)-related diseases such as deep vein thrombosis (DVT) is important to prevent irreversible or serious pathological conditions. However, the current way of diagnosing DVT is only possible after recognizing advanced DVT symptoms such as swelling, pain, and tightness in affected extremities, which may be due to the lack of information on neuromechanical changes following VC. Thus, the goal of this study was to investigate acute neuromechanical changes in muscle electrical activity and muscle stiffness when VC was induced. The eight pigs were selected and the change of muscle stiffness from the acceleration and muscle activity in terms of integral electromyography (IEMG) was investigated in three VC stages. Consequently, we discovered a significant increase in the change in muscle stiffness and IEMG from the baseline to the VC stages (p < 0.05). Our results and approach can enable early detection of pathological conditions associated with VC, which can be a basis for further developing early diagnostic tools for detecting VC-related diseases. English Public Library of Science Venous congestion affects neuromuscular changes in pigs in terms of muscle electrical activity and muscle stiffness Article 10.1371/journal.pone.0289266 1 PLoS ONE, v.18, no.8 PLoS ONE 18 8 Y scie scopus 001043333000035 2-s2.0-85166562604 Multidisciplinary Sciences Science & Technology - Other Topics Article INTRAMUSCULAR PRESSURE MANAGEMENT ISCHEMIA SIGNAL MODEL