Kim, Seunghwan Oh, Yong Suk Lee, Kwanghyoung Kim, Seongchan Maeng, Woo-Youl Kim, Kyung Su Kim, Ga-Been Cho, Seokjoo Han, Hyeonseok Park, Hyunwoo Wang, Mengqiu Avila, Raudel Xie, Zhaoqian Ko, Kabseok Choi, Jungrak Je, Minkyu Lee, Hyojin Lee, Sungho Koo, Jahyun Park, Inkyu 2024-01-19T09:03:30Z 2024-01-19T09:03:30Z 2023-05-11 2023-08 1613-6810 https://pubs.kist.re.kr/handle/201004/113473 Peripheral nerve injuries cause various disabilities related to loss of motor and sensory functions. The treatment of these injuries typically requires surgical operations for improving functional recovery of the nerve. However, capabilities for continuous nerve monitoring remain a challenge. Herein, a battery-free, wireless, cuff-type, implantable, multimodal physical sensing platform for continuous in vivo monitoring of temperature and strain from the injured nerve is introduced. The thin, soft temperature, and strain sensors wrapped around the nerve exhibit good sensitivity, excellent stability, high linearity, and minimum hysteresis in relevant ranges. In particular, the strain sensor integrated with circuits for temperature compensation provides reliable, accurate strain monitoring with negligible temperature dependence. The system enables power harvesting and data communication to wireless, multiple implanted devices wrapped around the nerve. Experimental evaluations, verified by numerical simulations, with animal tests, demonstrate the feasibility and stability of the sensor system, which has great potential for continuous in vivo nerve monitoring from an early stage to complete regeneration. English Wiley - V C H Verlag GmbbH & Co. Battery-Free, Wireless, Cuff-Type, Multimodal Physical Sensor for Continuous Temperature and Strain Monitoring of Nerve Article 10.1002/smll.202206839 1 Small, v.19, no.32 Small 19 32 N scie scopus 000973742000001 2-s2.0-85153297026 Chemistry, Multidisciplinary Chemistry, Physical Nanoscience & Nanotechnology Materials Science, Multidisciplinary Physics, Applied Physics, Condensed Matter Chemistry Science & Technology - Other Topics Materials Science Physics Article BLOOD-FLOW SCIATIC-NERVE CONDUCTION BLOCK OUTCOME MEASURES CRUSH INJURY REPAIR REGENERATION SOFT battery-free nerves strain sensors temperature sensors wireless