Kim Hyo-Jin Seung-Hoon Um Kang Yong Guk Shin Minwoo Jeon, Hojeong Kim Beop-Min 이득희 Yoon Kyungho 2024-01-19T09:30:12Z 2024-01-19T09:30:12Z 2023-11-02 2023-06 2288-4300 https://pubs.kist.re.kr/handle/201004/113615 This study aimed to develop a simulation model that accounts for skin-specific properties in order to predict photothermal damage during skin laser treatment. To construct a computational model, surface geometry information was obtained from an optical coherence tomography image, and the absorption coefficient of the skin was determined through spectrophotometry. The distribution of the internal light dose inside the skin medium was calculated using the light propagation model based on the Monte Carlo method. The photothermal response due to the absorption of laser light was modeled by a finite difference time domain model to solve the bio-heat transfer equation. The predicted depth and area of the damaged lesions from the simulation model were compared to those measured in ex vivo porcine skin. The present simulation model gave acceptable predictions with differences of approximately ∼10% in both depth and area. English 한국CDE학회 Laser-tissue interaction simulation considering skin-specific data to predict photothermal damage lesions during laser irradiation Article 10.1093/jcde/qwad033 1 Journal of Computational Design and Engineering, v.10, no.3, pp.947 - 958 Journal of Computational Design and Engineering 10 3 947 958 Y scie scopus kci ART003008402 000978555000001 2-s2.0-85159105617 Computer Science, Interdisciplinary Applications Engineering, Multidisciplinary Computer Science Engineering laser irradiation optical coherence tomography finite difference time-domain Monte Carlo simulation