Park, Byeongho Cha, Yeon Kyung Kwak, Jisung Hwang, Kyeong Seob Kim, Hyo-Suk Park, Subeen Pak, Yusin Park, Tai Hyun Song, Hyun Seok Kim, Jae Hun 2024-01-19T11:32:11Z 2024-01-19T11:32:11Z 2022-08-04 2022-08 1530-6984 https://pubs.kist.re.kr/handle/201004/114823 A photoreceptor on the retina acts as an optical waveguide to transfer an individual photonic signal to the cell inside, which is determined by the refractive index of internal materials. Under the photoactivation of photoreceptors making conformational and chemical variation in a visual cell, the optical signal modulation is demonstrated using an artificial photoreceptor-based waveguide with a controlling beam refraction. Two types of nanodiscs are made of human photoreceptor proteins, short-wavelength-sensitive opsin and rhodopsin, with spectral sensitivity. The refractive index and nonlinear features of those two photosensitive nanodiscs are investigated as fundamental properties. The photonanodiscs are photoactivated in such a way that allow refractive index tuning over 0.18 according to the biological function of the respective proteins with color-dependent response. English American Chemical Society Photosensitive Nanodiscs Composed of Human Photoreceptors for Refractive Index Modulation at Selective Wavelengths Article 10.1021/acs.nanolett.2c01685 1 Nano Letters, v.22, no.16, pp.6825 - 6832 Nano Letters 22 16 6825 6832 N scie scopus 000829283700001 Chemistry, Multidisciplinary Chemistry, Physical Nanoscience & Nanotechnology Materials Science, Multidisciplinary Physics, Applied Physics, Condensed Matter Chemistry Science & Technology - Other Topics Materials Science Physics Letter; Early Access WAVE-GUIDES FABRICATION RHODOPSIN SENSOR human photoreceptor nanodisc optical application refractive index modulation selective photoactivation