Ha, Siyoung Kim, Jinyeong Park, Chul Soon Lee, Sangwoo Yoo, Donggon Kim, Kyung Ho Seo, Sung Eun Park, Seon Joo An, Jai Eun Song, Hyun Seok Bae, Joonwon Kim, Woo-Keun Kwon, Oh Seok 2024-01-19T11:34:22Z 2024-01-19T11:34:22Z 2022-05-12 2022-07 0956-5663 https://pubs.kist.re.kr/handle/201004/114928 Due to the increase in drug-facilitated sexual assault (DFSA) enabled by the illegal use of drugs, there have been constant demands for simple methods that can be used to protect oneself against crime in real life. gamma-Hy-droxybutyric acid (GHB), a central nervous system depressant, is one of the most dangerous drugs for use in DFSA because it is colorless and has slow physiological effects, which pose challenges for developing in situ, realtime GHB monitoring techniques. In this study, we developed a method for in situ colorimetric GHB detection using various self-protection products (SPPs) coated with 2-(3-bromo-4-hydroxystyryl)-3-ethylbenzothiazol-3ium iodide (BHEI) as a chemical receptor embedded in hydrogels. Additionally, smartphone-based detection offers enhanced colorimetric sensitivity compared to that of the naked eye. The developed SPPs will help address drug-facilitated social problems. English Pergamon Press Ltd. In situ, real-time, colorimetric detection of γ-hydroxybutyric acid (GHB) using self-protection products coated with chemical receptor-embedded hydrogel Article 10.1016/j.bios.2022.114195 1 Biosensors and Bioelectronics, v.207 Biosensors and Bioelectronics 207 Y scie scopus 000789670000003 Biophysics Biotechnology & Applied Microbiology Chemistry, Analytical Electrochemistry Nanoscience & Nanotechnology Biophysics Biotechnology & Applied Microbiology Chemistry Electrochemistry Science & Technology - Other Topics Article DATE-RAPE DRUG GAMMA-HYDROXYBUTYRATE FLUORESCENT SENSOR WINDOW URINE SERUM gamma-Hydroxybutyric acid(GHB) Drug-facilitated sexual assault(DFSA) Self-protection product(SPP) In-situ colorimetric detection Chemical receptor