Chae, Uikyu Shin, Hyoguen Lee, Hyuqjoo Jenny Lee, Jnngpyo Choi, Nakwon Lee, Yi Jae Lee, Soo Hyun Woo, Jiwan Cho, Yakdol Yoon, Eui-Sung Yu, Hyun-Yong Cho, Il-Joo 2024-01-19T11:37:50Z 2024-01-19T11:37:50Z 2022-03-01 2016-02-29 1084-6999 https://pubs.kist.re.kr/handle/201004/114964 We present a new MEMS neural probe integrated with two microfluidic channels, a mixer, and biosensors for real-time monitoring of neurochemicals and neural activities. The microfluidic channels for push-pull operation of fluids enable infusion of drugs and extraction of brain fluid at the same time. Also, we can simultaneously monitor neural activities modulated by the infused drug. The real-time monitoring of neurochemicals using the monolithically integrated sensors is a new concept we propose which is enabled through the MEMS technology. The proposed system will provide an important new set of information for brain disease investigation and functional brain-mapping. English IEEE A NEW MEMS NEURAL PROBE SYSTEM INTEGRATED WITH PUSH-PULL MICROFLUIDIC CHANNELS AND BIOSENSORS FOR REAL-TIME MONITORING OF NEUROCHEMICALS Conference 1 29th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp.329 - 332 29th IEEE International Conference on Micro Electro Mechanical Systems (MEMS) 329 332 US Shanghai, PEOPLES R CHINA 2016-01-24 2016 IEEE 29TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS) 000381797300087 2-s2.0-84970998489