Kang, Ji Eun Yoo, Nayeon Jeon, Byeong Jun Kim, Beom Seok Chung, Eui-Hwan 2024-01-19T12:02:07Z 2024-01-19T12:02:07Z 2022-06-30 2022-05 1664-462X https://pubs.kist.re.kr/handle/201004/115188 Antibiotic resistance has become increasingly prevalent in the environment. Many alternative strategies have been proposed for the treatment and prevention of diverse diseases in agriculture. Among them, the modulation of bacterial virulence to bypass antibiotic resistance or boost plant innate immunity can be considered a promising drug target. Plant-produced natural products offer a broad spectrum of stereochemistry and a wide range of pharmacophores, providing a great diversity of biological activities. Here, we present a perspective on the putative role of plant-produced resveratrol oligomers as anti-virulence and plant-immune priming agents for efficient disease management. Resveratrol oligomers can decrease (1) bacterial motility directly and (2) indirectly by attenuating the bacterial type III secretion system (TT3S). They induce enhanced local immune responses mediated by two-layered plant innate immunity, demonstrating (3) a putative plant immune priming role. English FRONTIERS MEDIA SA Resveratrol Oligomers, Plant-Produced Natural Products With Anti-virulence and Plant Immune-Priming Roles Article 10.3389/fpls.2022.885625 1 FRONTIERS IN PLANT SCIENCE, v.13 FRONTIERS IN PLANT SCIENCE 13 Y scie scopus 000811341100001 Plant Sciences Plant Sciences Article PSEUDOMONAS-SYRINGAE DEFENSE RESPONSES BIOFILM FORMATION BOTRYTIS-CINEREA TOMATO PLANTS RESISTANCE ACID ARABIDOPSIS STILBENOIDS GRAPEVINE anti-virulence immune-priming type III secretion system (TT3S) resveratrol oligomers stilbene