Im, Seung Hyuk Im, Dam Hyeok Park, Su Jeong Jung, Youngmee Kim, Dong-Hwee Kim, Soo Hyun 2024-01-19T12:03:05Z 2024-01-19T12:03:05Z 2022-04-29 2022-05 0079-6425 https://pubs.kist.re.kr/handle/201004/115240 Cardiovascular disease (CVD) has emerged as a severe illness worldwide. Currently, the top ten causes of death in the world include ischemic heart disease according to the Global Health Observatory data provided by the World Health Organization (WHO). To treat the CVD, percutaneous coronary intervention (PCI) has been used in clinical treatment. Unfortunately, CVD is still considered a serious illness for human health, even though the mortality due to CVD has reduced compared to the time before the availability of PCI procedure. Since the implantation of the bare metal stent in humans as the first-generation stent, drug-eluting and biodegradable stents have been developed as the second-and third-generation stents to address the drawbacks of previously developed stents. Currently, various types of stents with different geometries, structures, backbone materials, and other properties have been developed, but identifying the best stent for superior clinical efficacy is still difficult. To address this issue, this review classifies the vascular stents according to four types of scaffold materials: non-degradable metal, degradable metal, nondegradable polymer, and degradable polymer. Additionally, majority of the vascular stents withvarious merits and demerits that have been developed till date are discussed with focus on the critical requirements for next-generation stents. English Pergamon Press Ltd. Current status and future direction of metallic and polymeric materials for advanced vascular stents Article 10.1016/j.pmatsci.2022.100922 1 Progress in Materials Science, v.126 Progress in Materials Science 126 Y scie scopus 000773909900001 2-s2.0-85123188513 Materials Science, Multidisciplinary Materials Science Review DE-NOVO LESIONS OPTICAL COHERENCE TOMOGRAPHY ABLUMINAL BIODEGRADABLE POLYMER INTRAVASCULAR ULTRASOUND ANALYSIS RANDOMIZED CONTROLLED-TRIAL ANGIOGRAPHIC FOLLOW-UP COBALT-CHROMIUM ALLOY SIROLIMUS-ELUTING STENT CORONARY-ARTERY-DISEASE SUPERFICIAL FEMORAL-ARTERY Coronary artery disease Polymeric stent Metallic stent Biodegradable stent Drug-eluting stent Next-generation stents