Kim, Hyoung-Ho Kim, Kyung-Wuk Lee, Changje Choi, Young Ho Kim, Min Uk Baba, Yasutaka 2024-01-19T13:31:20Z 2024-01-19T13:31:20Z 2022-01-25 2021-11 1229-6929 https://pubs.kist.re.kr/handle/201004/116169 Objective: To analyze the computational fluid dynamics (CFD) of femoral artery pseudoaneurysm (FAP), identify a suitable location and timing for percutaneous thrombin injection (PTI) based on this analysis, and report our clinical experience with the procedure. Materials and Methods: CFD can be used to analyze the hemodynamics of the human body. An analysis using CFD recommended that the suitable location of the needle tip for PTI is at the center of the aneurysm sac and the optimal timing for starting PTI is during the early inflow phase of blood into the sac. Since 2011, seven patients (three male and four female; median age, 60 years [range, 43-75 years]) with FAP were treated with PTI based on the devised suitable location and time. Prior to the procedure, color Doppler ultrasonography was performed to determine the location and timing of the thrombin injection. Results: The technical success rate of the PTI was 100%. The amount of thrombin used for the procedure ranged from 200 IU to 1000 IU (median, 500 IU). None of the patients experienced any symptoms or signs of embolic complications during the procedure. Follow-up CT images did not reveal any embolism in the lower extremities and showed complete thrombosis of the pseudoaneurysm. Conclusion: Based on our study of CFD, PTI administered centrally in the FAP during early inflow, as seen on color Doppler, can be an effective technique. English KOREAN RADIOLOGICAL SOC Percutaneous Thrombin Injection Based on Computational Fluid Dynamics of Femoral Artery Pseudoaneurysms Article 10.3348/kjr.2020.1340 1 KOREAN JOURNAL OF RADIOLOGY, v.22, no.11, pp.1834 - 1840 KOREAN JOURNAL OF RADIOLOGY 22 11 1834 1840 Y scie scopus kci ART002766870 000714039800009 2-s2.0-85112688526 Radiology, Nuclear Medicine & Medical Imaging Radiology, Nuclear Medicine & Medical Imaging Article CFD Femoral artery False aneurysm Thrombin Injections