Moon, Kyoung Mi Lee, Min-Kyeong Hwang, Taehyeok Choi, Chun Whan Kim, Min Soo Kim, Hyeung-Rak Lee, Bonggi 2024-01-19T13:34:17Z 2024-01-19T13:34:17Z 2021-10-21 2021-10 2213-2317 https://pubs.kist.re.kr/handle/201004/116357 Forkhead box, class O (FoxO) family members are multifunctional transcription factors that are involved in several metabolic processes, including energy metabolism, apoptosis, DNA repair, and oxidative stress. However, their roles in skin health have not been well-documented. Recent studies have indicated that FoxOs are important factors to control skin homeostasis and health. The activation or deactivation of some FoxO family members is closely related to melanogenesis, wound healing, acne, and melanoma. In this review, we have discussed the recent findings that demonstrate the relationship between FoxOs and skin health as well as the underlying mechanisms associated with their functions. English ELSEVIER TRANSCRIPTION FACTOR FOXO3A ENDOTHELIAL GROWTH-FACTOR OXIDATIVE STRESS MELANOMA-CELLS MAMMALIAN TARGET POTENTIAL ROLE ACNE-VULGARIS TNF-ALPHA FACTOR-I EXPRESSION The multi-functional roles of forkhead box protein O in skin aging and diseases Article 10.1016/j.redox.2021.102101 1 REDOX BIOLOGY, v.46 REDOX BIOLOGY 46 scie scopus 000702852100001 2-s2.0-85112811743 Biochemistry & Molecular Biology Biochemistry & Molecular Biology Article TRANSCRIPTION FACTOR FOXO3A ENDOTHELIAL GROWTH-FACTOR OXIDATIVE STRESS MELANOMA-CELLS MAMMALIAN TARGET POTENTIAL ROLE ACNE-VULGARIS TNF-ALPHA FACTOR-I EXPRESSION FoxOs Melanogenesis Wound healing Acne Melanoma