Kim, Hayom Kang, Sung Hoon Kim, Soon Ho Kim, Seong Hwan Hwang, Jihyeon Kim, Jae-Gyum Han, Kyungreem Kim, Jung Bin 2024-01-19T14:30:31Z 2024-01-19T14:30:31Z 2021-10-21 2021-07 2045-2322 https://pubs.kist.re.kr/handle/201004/116795 The purpose of this study was to identify the mechanisms underlying effects of coffee on cognition in the context of brain networks. Here we investigated functional connectivity before and after drinking coffee using graph-theoretic analysis of electroencephalography (EEG). Twenty-one healthy adults voluntarily participated in this study. The resting-state EEG data and results of neuropsychological tests were consecutively acquired before and 30 min after coffee consumption. Graph analyses were performed and compared before and after coffee consumption. Correlation analyses were conducted to assess the relationship between changes in graph measures and those in cognitive function tests. Functional connectivity (FC) was reorganized toward more efficient network properties after coffee consumption. Performance in Digit Span tests and Trail Making Test Part B improved after coffee consumption, and the improved performance in executive function was correlated with changes in graph measures, reflecting a shift toward efficient network properties. The beneficial effects of coffee on cognitive function might be attributed to the reorganization of FC toward more efficient network properties. Based on our findings, the patterns of network reorganization could be used as quantitative markers to elucidate the mechanisms underlying the beneficial effects of coffee on cognition, especially executive function. English Nature Publishing Group Drinking coffee enhances neurocognitive function by reorganizing brain functional connectivity Article 10.1038/s41598-021-93849-7 1 Scientific Reports, v.11, no.1 Scientific Reports 11 1 Y scie scopus 000675273800020 2-s2.0-85111107435 Multidisciplinary Sciences Science & Technology - Other Topics Article CAFFEINE TRAIL PERFORMANCE MEMORY TASK ACTIVATION ATTENTION STROOP MOOD FMRI