Kumari, Nitee Kumar, Sumit Karmacharya, Mamata Dubbu, Sateesh Kwon, Taewan Singh, Varsha Chae, Keun Hwa Kumar, Amit Cho, Yoon-Kyoung Lee, In Su 2024-01-19T15:33:11Z 2024-01-19T15:33:11Z 2022-01-10 2021-01-13 1530-6984 https://pubs.kist.re.kr/handle/201004/117532 Next-generation catalysts are urgently needed to tackle the global challenge of antimicrobial resistance. Existing antimicrobials cannot function in the complex and stressful chemical conditions found in biofilms, and as a result, they are unable to infiltrate, diffuse into, and eradicate the biofilm and its associated matrix. Here, we introduce mixed-FeCo-oxide-based surface-textured nanostructures (MTex) as highly efficient magneto-catalytic platforms. These systems can produce defensive ROS over a broad pH range and can effectively diffuse into the biofilm and kill the embedded bacteria. Because the nanostructures are magnetic, biofilm debris can be scraped out of the microchannels. The key antifouling efficacy of MTex originates from the unique surface topography that resembles that of a ploughed field. These are captured as stable textured intermediates during the oxidative annealing and solid-state conversion of beta-FeOOH nanocrystals. These nanoscale surfaces will advance progress toward developing a broad array of new enzyme-like properties at the nanobio interface. English AMER CHEMICAL SOC X-RAY-ABSORPTION NANOPARTICLES ENZYME BACTERIA THERAPY Surface-Textured Mixed-Metal-Oxide Nanocrystals as Efficient Catalysts for ROS Production and Biofilm Eradication Article 10.1021/acs.nanolett.0c03639 1 NANO LETTERS, v.21, no.1, pp.279 - 287 NANO LETTERS 21 1 279 287 scie scopus 000611082000039 2-s2.0-85098762604 Chemistry, Multidisciplinary Chemistry, Physical Nanoscience & Nanotechnology Materials Science, Multidisciplinary Physics, Applied Physics, Condensed Matter Chemistry Science & Technology - Other Topics Materials Science Physics Article X-RAY-ABSORPTION NANOPARTICLES ENZYME BACTERIA THERAPY Metal oxide ROS Antimicrobial agent Biofilm removal Nanocatalyst