Kim, Hyeohn Bang, Kyeong-Mi Ha, Heonjin Cho, Nam Heon Namgung, Seok Daniel Im, Sang Won Cho, Kang Hee Kim, Ryeong Myeong Il Choi, Won Lim, Yae-Chan Shin, Ji-Yeon Song, Hyun Kyu Kim, Nak-Kyoon Nam, Ki Tae 2024-01-19T15:34:06Z 2024-01-19T15:34:06Z 2021-10-21 2021-01 1936-0851 https://pubs.kist.re.kr/handle/201004/117584 Chiral inorganic nanomaterials have revealed opportunities in various fields owing to their strong light-matter interactions. In particular, chiral metal oxide nanomaterials that can control light and biochemical reactions have been highlighted due to their catalytic activity and biocompatibility. In this study, we present the synthesis of chiral cobalt oxide nanoparticles with a g-factor of 0.01 in the UV-visible region using L- and D-Tyr-Tyr-Cys ligands. The conformation of the Tyr-Tyr-Cys peptide on the nanoparticle surfaces was identified by 2D NMR spectroscopy analysis. In addition, the sequence effect of Tyr-Tyr-Cys developing chiral nanoparticles was analyzed. The revealed peptide structure, along with the experimental results, demonstrate the important role of the thiol group and carboxyl group of the Tyr-Tyr-Cys ligand in chirality evolution. Importantly, due to the magnetic properties of chiral cobalt oxide nanoparticles and their strong absorption in the UV region, the circular dichroism (CD) responses can be dramatically modulated under an external magnetic field. English American Chemical Society Tyrosyltyrosylcysteine-Directed Synthesis of Chiral Cobalt Oxide Nanoparticles and Peptide Conformation Analysis Article 10.1021/acsnano.0c07655 1 ACS Nano, v.15, no.1, pp.979 - 988 ACS Nano 15 1 979 988 N scie scopus 000613942700073 2-s2.0-85098763152 Chemistry, Multidisciplinary Chemistry, Physical Nanoscience & Nanotechnology Materials Science, Multidisciplinary Chemistry Science & Technology - Other Topics Materials Science Article chirality cobalt oxide nanoparticle Tyr-Tyr-Cys peptide ligand magnetic circular dichroism NMR