Lee, Inae Seok, Youngung Jung, Huijin Yang, Byungjin Lee, Jiho Kim, Jaeyoung Pyo, Heesoo Song, Chang-Seon Choi, Won Kim, Min-Gon Lee, Joonseok 2024-01-19T16:00:45Z 2024-01-19T16:00:45Z 2021-09-02 2020-12-24 2379-3694 https://pubs.kist.re.kr/handle/201004/117667 Airborne pathogens causing infectious diseases are often highly transmittable between humans. Therefore, an airborne pathogen-monitoring system capable of on-site detection and identification would aid tremendously in preventing and controlling the early stages of pathogen spread. Here, we describe an integrated sampling/monitoring platform for on-site and real-time detection of airborne viruses. We used MS2 bacteriophage and avian influenza virus (AIV) H1N1 to evaluate bioaerosol sampling and detection performance of the platform. Our results show that, within 20 min, aerosolized viruses can be detected using the signal of near-infrared (NIR)-to-NIR nanoprobes. The pretreatment of the sampling pad improved the transfer efficiency of MS2 viruses to the detection zone, compared to an untreated pad. Our platform could detect concentrations as low as 10(4.)(294) 50% egg infectious dose (EID50)/m(3) AIVs collected from a cloacal swab sample (10(4.)(838) EID50/mL). These results indicate that our sampling/monitoring platform could be applied for the early detection of biological hazards in various fields. English AMER CHEMICAL SOC INFLUENZA-VIRUS FLOW BACTERIA INDOOR ASSAY AIR Integrated Bioaerosol Sampling/Monitoring Platform: Field-Deployable and Rapid Detection of Airborne Viruses Article 10.1021/acssensors.0c01531 1 ACS Sensors, v.5, no.12, pp.3915 - 3922 ACS Sensors 5 12 3915 3922 scie scopus 000603403600020 2-s2.0-85095868844 Chemistry, Multidisciplinary Chemistry, Analytical Nanoscience & Nanotechnology Chemistry Science & Technology - Other Topics Article INFLUENZA-VIRUS FLOW BACTERIA INDOOR ASSAY AIR airborne pathogen influenza virus rapid detection nanoprobe lateral flow immunoassay