Kim, Jisoo Kim, Chaewoo Han, Hio-Been Cho, Cheol Jun Yeom, Wooseob Lee, Sung Q. Choi, Jee Hyun 2024-01-19T16:02:51Z 2024-01-19T16:02:51Z 2021-09-02 2020-12 https://pubs.kist.re.kr/handle/201004/117796 Social cognition requires neural processing, yet a unifying method linking particular brain activities and social behaviors is lacking. Here, we embedded mobile edge computing (MEC) and light emitting diodes (LEDs) on a neurotelemetry headstage, such that a particular neural event of interest is processed by the MEC and subsequently an LED is illuminated, allowing simultaneous temporospatial visualization of that neural event in multiple, socially interacting mice. As a proof of concept, we configured our system to illuminate an LED in response to gamma oscillations in the basolateral amygdala (BLA gamma) in freely moving mice. We identified (i) BLA gamma responses to a spider robot, (ii) affect-related BLA gamma during conflict, and (iii) formation of defensive aggregation under a threat by the robot, and reduction of BLA gamma responses in the inner-located mice. Our system can provide an intuitive framework for examining brain-behavior connections in various ecological situations and population structures. English American Association for the Advancement of Science A bird's-eye view of brain activity in socially interacting mice through mobile edge computing (MEC) Article 10.1126/sciadv.abb9841 1 Science Advances, v.6, no.49 Science Advances 6 49 Y scie scopus 000596477400015 2-s2.0-85097121253 Multidisciplinary Sciences Science & Technology - Other Topics Article GAMMA OSCILLATIONS COORDINATE AMYGDALA FEAR INFORMATION DYNAMICS IOT