Aflatoonian, Mohammad Reza Tajik, Somayeh Aflatoonian, Behnaz Beitollahi, Hadi Zhang, Kaiqiang Van Le, Quyet Cha, Joo Hwan Jang, Ho Won Shokouhimehr, Mohammadreza Peng, Wanxi 2024-01-19T16:03:11Z 2024-01-19T16:03:11Z 2021-09-02 2020-11-30 2296-2646 https://pubs.kist.re.kr/handle/201004/117817 In this paper, graphene (Gr)/Co3O4 nanocomposite was synthesized and utilized for the development of a novel electrochemical sensor to detect tramadol. Tramadol determination was examined by linear sweep voltammetry, differential pulse voltammetry, cyclic voltammetry, and chronoamperometry on Gr/Co3O4 nanocomposite-modified screen-printed electrode (Gr/Co3O4/SPE) in phosphate-buffered saline (PBS). Under the optimized condition, the detection limit of tramadol is 0.03 mu M (S/N = 3) in the linear ranges of 0.1-500.0 mu M. Furthermore, Gr/Co3O4/SPE was satisfactorily utilized to detect tramadol in tramadol tablet and urine specimens. English FRONTIERS MEDIA SA GLASSY-CARBON ELECTRODE VOLTAMMETRIC DETERMINATION AMPEROMETRIC DETECTION SENSOR PARACETAMOL NANOPARTICLES NANOTUBES PRECONCENTRATION EPINEPHRINE BIOSENSORS A Screen-Printed Electrode Modified With Graphene/Co3O4 Nanocomposite for Electrochemical Detection of Tramadol Article 10.3389/fchem.2020.562308 1 FRONTIERS IN CHEMISTRY, v.8 FRONTIERS IN CHEMISTRY 8 scie scopus 000598153300001 2-s2.0-85097597029 Chemistry, Multidisciplinary Chemistry Article GLASSY-CARBON ELECTRODE VOLTAMMETRIC DETERMINATION AMPEROMETRIC DETECTION SENSOR PARACETAMOL NANOPARTICLES NANOTUBES PRECONCENTRATION EPINEPHRINE BIOSENSORS electrochemical sensor tramadol graphene Co3O4 nanocomposite screen printed electrode nanomaterials