Viet Phuong Nguyen Yoo, Jin Lee, Ju Young Chung, Justin J. Hwang, Jeong Ho Jung, Youngmee Lee, Seung-Mo 2024-01-19T16:32:55Z 2024-01-19T16:32:55Z 2021-09-02 2020-09-30 1944-8244 https://pubs.kist.re.kr/handle/201004/118089 Biodegradable polymers have been often used in place of conventional nondegradable polymers for industrial and medical applications. In particular, polylactide (PLA) has been regarded as a popular ecofriendly plastic and has many advantages like good biocompatibility and processability. Yet, it still has some drawbacks in mechanical properties. Here, we prepared Ti-infiltrated PLA by mimicking the gelatinous jaw of a seaworm whose mechanical properties are toggled up and down by the tiny amount of metal ions, expecting to prepare a new type of alternative. Ti induced significant chemical and microstructural changes in the PLA, which led to a notable improvement in the mechanical properties as compared to the neat PLA. The Ti-infiltrated PLA exhibited high resistance to rapid degradation. More importantly, the toxicity assessment demonstrated that the resulting PLA is still biocompatible and nontoxic. Consequently, we proved that the Ti-infiltrated PLA has high mechanical properties comparable to conventional nondegradable polymers and good biocompatibility as well as delayed biodegradability. We anticipate the current Ti-infiltrated PLA to be an ecofriendly replacement of some conventional plastics, which helps preserve a green environment. English American Chemical Society MASSIVE POLY(ALPHA-HYDROXY ACIDS) HYDROLYTIC DEGRADATION COMPOSITES BLENDS NEREIS ZINC PLA Enhanced Mechanical Stability and Biodegradability of Ti-Infiltrated Polylactide Article 10.1021/acsami.0c13246 1 ACS Applied Materials & Interfaces, v.12, no.39, pp.43501 - 43512 ACS Applied Materials & Interfaces 12 39 43501 43512 scie scopus 000577111700015 2-s2.0-85092681954 Nanoscience & Nanotechnology Materials Science, Multidisciplinary Science & Technology - Other Topics Materials Science Article MASSIVE POLY(ALPHA-HYDROXY ACIDS) HYDROLYTIC DEGRADATION COMPOSITES BLENDS NEREIS ZINC PLA polylactide (PLA) atomic layer deposition (ALD) metal infiltration biocompatibility biodegradation mechanical property