Phyo, Sooyeol Choi, Sung Jang, Jaeheok Choi, Sun Lee, Jiwon 2024-01-19T16:33:16Z 2024-01-19T16:33:16Z 2021-09-02 2020-09-21 1473-0197 https://pubs.kist.re.kr/handle/201004/118110 In this work, a 3D-printed metal column was developed for micro gas chromatography (GC) applications and its properties and gas separation performances were characterized. By using a Ti6Al4V grade 23 powder, a square spiral one meter-long column (3D-column) was 3D-printed on a planar substrate of 3.4 x 3.3 x 0.2 cm and then perhydropolysilazane (PHPS) was deposited as a pre-treatment agent, followed by a coating of stationary phase (OV-1) onto the inner wall of the micro-channel. The 500 mu m-diameter circular channel and two 800 mu m-wide ports of the 3D-column were confirmed to be uniform by 3D X-ray microscopy without any distortion. The physical and thermal properties of the 3D-column were found to be very similar to that of the standard Ti6Al4V grade 23 alloy with near zero porosity (similar to 0.07%). The 3D-column with pre-treatment and stationary coating demonstrated efficient separation performance of gas mixtures containing alkanes, aromatics, alcohols, and ketones compared to a bare or only pretreated 3D-column in terms of the peak shape, broadening, and resolution (R> 1) within 2-3 min. The well-matched thermal responses to the target temperatures were demonstrated at the ramping rates of 10-20 degrees C min(-1)upto 200 degrees C with uniform heat distribution over the 3D-column. In addition, the column bleed profiles showed that the 3D-column with PHPS had a 71% lower baseline intensity at 350 degrees C than that without PHPS. The 3D-column was then employed to separate a gas mixture of twelve alkanes (C9-C18, C22, C24) without any significant column bleeding and peak tailing. Therefore, the thermal responses and stability of the 3D-column promise its applicability in high temperature GC applications. English Royal Society of Chemistry FABRICATION CAPILLARY AIR TEMPERATURE STRESS GC A 3D-printed metal column for micro gas chromatography Article 10.1039/d0lc00540a 1 Lab on a Chip, v.20, no.18, pp.3435 - 3444 Lab on a Chip 20 18 3435 3444 scie scopus 000569507600010 2-s2.0-85091127363 Biochemical Research Methods Chemistry, Multidisciplinary Chemistry, Analytical Nanoscience & Nanotechnology Instruments & Instrumentation Biochemistry & Molecular Biology Chemistry Science & Technology - Other Topics Instruments & Instrumentation Article FABRICATION CAPILLARY AIR TEMPERATURE STRESS GC