Cui, Junjie Kim, Gayoung Kim, Sehoon Kwon, Ji Eon Park, Soo Young 2024-01-19T17:31:56Z 2024-01-19T17:31:56Z 2021-09-05 2020-06 2367-0932 https://pubs.kist.re.kr/handle/201004/118585 We synthesized an amphiphilic small molecule 1 by attaching oligo(ethylene glycol) (OEG) and N,N-diethylamine (DEA) units to a fluorescent dicyanodistyrylbenzene (DCS) core. The molecule is fully soluble in aqueous solution at low pH (pH<4.3) by protonation of the DEA groups; but, above pH 4.3, it self-assembles to form nanoparticles due to increased hydrophobicity upon deprotonation, leading to a ratiometric fluorescence color change from green emission in the monomeric form (lambda(em,max)=538 nm) to red emission in the aggregated form (lambda(em,max)=646 nm). It should be noted that the ratio of emission intensities at 538 nm and 646 nm (R=I-538/I-646) changes drastically about 42-fold within a very narrow pH range of 4.3-4.6. English WILEY-V C H VERLAG GMBH INTRACELLULAR PH RANGE DESIGN NANOFIBERS VALUES SENSOR WATER Ultra-pH-Sensitive Small Molecule Probe Showing a Ratiometric Fluorescence Color Change Article 10.1002/cptc.202000023 1 CHEMPHOTOCHEM, v.4, no.6, pp.393 - 397 CHEMPHOTOCHEM 4 6 393 397 scie scopus 000514242900001 2-s2.0-85086151982 Chemistry, Physical Chemistry Article INTRACELLULAR PH RANGE DESIGN NANOFIBERS VALUES SENSOR WATER amphiphiles bioimaging fluorescence switching pH responsiveness self-assembly supramolecular chemistry