Kang, Jeong Wook Kim, Myung Gu Kim, Sung Su Im, Heh-In Dong, Sung Hwa Kim, Sang Hoon Yeo, Seung Geun 2024-01-19T17:34:40Z 2024-01-19T17:34:40Z 2021-09-05 2020-04-02 0001-6489 https://pubs.kist.re.kr/handle/201004/118742 Background: Neutrophil-to-lymphocyte ratio (NLR) has emerged as a marker for degree of inflammation. Inflammation has been regarded as one of the causes of idiopathic sudden sensorineural hearing loss. Objectives: This study investigated the potential association between neutrophil-to-lymphocyte ratio (NLR) and prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). Material and methods: This retrospective, case-control clinical trial analyzed data from 186 subjects diagnosed with ISSNHL and admitted to Kyung-Hee Medical Center between March 2016 and February 2019. Hematologic and audiometric parameters were measured. Results: NLR showed a linear correlation with hearing recovery in patients with ISSNHL, with hearing gain (dB) = 56.698 - 3.718 x NLR (r(2) = 0.451, p = .001). Hearing recovery at all frequencies was numerically higher in patients with low (<6.661) than higher (>= 6.661) NLR at all frequencies and was significantly higher at 500, 1000, 2000, 3000, and 4000 Hz. Hearing thresholds at 250, 500, 1000, 2000, 3000, and 4000 Hz in the low NLR group were significantly lower after treatment. English TAYLOR & FRANCIS LTD FOLLOW-UP POPULATION Neutrophil-lymphocyte ratio as a valuable prognostic marker in idiopathic sudden sensorineural hearing loss Article 10.1080/00016489.2019.1705998 1 ACTA OTO-LARYNGOLOGICA, v.140, no.4, pp.307 - 313 ACTA OTO-LARYNGOLOGICA 140 4 307 313 scie scopus 000504393800001 2-s2.0-85077374431 Otorhinolaryngology Otorhinolaryngology Article FOLLOW-UP POPULATION Neutrophil-lymphocyte ratio idiopathic sudden sensorineural hearing loss Prognosis Marker