Kim, Jeong Do Kang, Ji Eun Kim, Beom Seok 2024-01-19T18:01:10Z 2024-01-19T18:01:10Z 2021-09-04 2020-04 0925-5214 https://pubs.kist.re.kr/handle/201004/118825 Microbial secondary metabolites have been a valuable source of antifungal compounds for the fungicide industry to develop plant disease control agents. In order to find natural antifungal compounds useful for the control of Botrytis cinerea causing postharvest gray mold, we screened microbial culture extracts and found the extract of Streptomyces plumbeus strain CA5 which was isolated from the soil sample of Chuncheon Province. The cell extract of CA5 strain markedly reduced the disease incidence of gray mold on grapes to a value of 22.2 % while the non-treated control showed 100 % disease incidence. The active ingredient (CASA) was identified from the cell extract of CA5 strain using a variety of chromatographic methods and spectroscopic analyses. The structure of CASA was determined to be the polyene macrolide lucensomycin. Lucensomycin showed inhibitory effects against the spores of B. cinerea at a concentration as low as 1 mg L-1 and completely inhibited gray mold development on grapes at a concentration of 100 mg L-1. English Elsevier BV Postharvest disease control efficacy of the polyene macrolide lucensomycin produced by Streptomyces plumbeus strain CA5 against gray mold on grapes Article 10.1016/j.postharvbio.2019.111115 1 Postharvest Biology and Technology, v.162 Postharvest Biology and Technology 162 N scie scopus 000508903600016 2-s2.0-85077240912 Agronomy Food Science & Technology Horticulture Agriculture Food Science & Technology Article BIOLOGICAL-CONTROL BOTRYTIS-CINEREA AMPHOTERICIN-B TABLE GRAPES BIOCONTROL RESISTANCE BACILLUS AGENTS ANTIBIOTICS FUNGICIDES Antagonistic actinomycete Gray mold Polyene macrolide Biofungicides Lucensomycin Postharvest disease