Kim, Younghye Park, Gyeong Do Balamurugan, Mani Seo, Jiwon Min, Byoung Koun Nam, Ki Tae 2024-01-19T18:04:27Z 2024-01-19T18:04:27Z 2021-09-05 2020-02 2198-3844 https://pubs.kist.re.kr/handle/201004/119012 The carboxylation of hydrocarbons using CO2 as a one-carbon building block is an attractive route for the synthesis of carboxylic acids and their derivatives. Until now, chemical carboxylation catalyzed by organometallic nucleophiles and reductants has been generally adopted particularly for the precise selectivity control of carboxylation sites. As another approach, electrochemical carboxylation has been attempted but these carboxylation reactions are limited to only a few pathways. In the case of styrene, dicarboxylation at the alpha- and beta-positions is mostly observed with electrochemical carboxylation while site-selective hydrocarboxylations are hardly achieved. In this study, electrochemical beta-selective hydrocarboxylation of styrene using CO2 and water is developed, in which the site selectivity can be precisely controlled between beta-hydrocarboxylation and dicarboxylation without the aid of homogeneous catalysts. In this platform, water is used as proton source in the beta-hydrocarboxylation of styrene where its addition results in significant enhancement of the selectivity toward beta-hydrocarboxylation. This work provides insights into new strategies for site-selectivity-controllable carboxylation with CO2 using an electrochemical platform. English WILEY CARBON-DIOXIDE REGIOSELECTIVE HYDROCARBOXYLATION CATALYZED HYDROCARBOXYLATION UNSATURATED-HYDROCARBONS SUBSTITUTED ALKENES CARBOXYLIC-ACIDS SIMPLE ALCOHOLS NICKEL ALKYNES REDUCTION Electrochemical beta-Selective Hydrocarboxylation of Styrene Using CO2 and Water Article 10.1002/advs.201900137 1 ADVANCED SCIENCE, v.7, no.3 ADVANCED SCIENCE 7 3 scie scopus 000502896700001 2-s2.0-85076754179 Chemistry, Multidisciplinary Nanoscience & Nanotechnology Materials Science, Multidisciplinary Chemistry Science & Technology - Other Topics Materials Science Article CARBON-DIOXIDE REGIOSELECTIVE HYDROCARBOXYLATION CATALYZED HYDROCARBOXYLATION UNSATURATED-HYDROCARBONS SUBSTITUTED ALKENES CARBOXYLIC-ACIDS SIMPLE ALCOHOLS NICKEL ALKYNES REDUCTION carbon fixation carboxylation CO2 reduction electrochemistry