Lee, Soul-Hee Kim, Myung Jong Ahn, Seokhoon Koh, Byumseok 2024-01-19T18:04:28Z 2024-01-19T18:04:28Z 2021-09-05 2020-02 1661-6596 https://pubs.kist.re.kr/handle/201004/119013 Commercially available boron nitride nanotubes (BNNTs) and their purified form (pBNNTs) were dispersed in aqueous solutions with various dispersants, and their cytotoxicity and drug encapsulation capacity were monitored. Our data suggest that pBNNTs showed an average increase in dispersibility of 37.3% in aqueous solution in the presence of 10 different dispersants. In addition, 100 mu g of pBNNTs induced an average decrease in cytotoxicity of 27.4% compared to same amount of BNNTs in normal cell lines. The same amount of pBNNTs can encapsulate 10.4-fold more drug (camptothecin) compared to BNNTs. These data suggest that the purification of BNNTs improves several of their properties, which can be applied to biological experiments and are thus essential in the biological application of BNNTs. English MDPI ANTICANCER DRUG HIGH-PURITY DELIVERY CARBON ENCAPSULATION DISPERSION YIELD Purification of Boron Nitride Nanotubes Enhances Biological Application Properties Article 10.3390/ijms21041529 1 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.21, no.4 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21 4 scie scopus 000522524400356 2-s2.0-85079844273 Biochemistry & Molecular Biology Chemistry, Multidisciplinary Biochemistry & Molecular Biology Chemistry Article ANTICANCER DRUG HIGH-PURITY DELIVERY CARBON ENCAPSULATION DISPERSION YIELD boron nitride nanotube purification encapsulation dispersion