Oh, Jungkyun Yang, Heehong Jeong, Go Een Moon, Dongseok Kwon, Oh Seok Phyo, Sooyeol Lee, Jiwon Song, Hyun Seok Park, Tai Hyun Jang, Jyongsik 2024-01-19T19:02:49Z 2024-01-19T19:02:49Z 2021-09-04 2019-10-01 0003-2700 https://pubs.kist.re.kr/handle/201004/119481 Field-effect transistor (FET) devices based on conductive nanomaterials have been used to develop biosensors. However, development of FET-based biosensors that allow efficient stability, especially in the gas phase, for obtaining reliable and reproducible responses remains a challenge. In this study, we developed a nanodisc (ND)-functionalized bioelectronic nose (NBN) based on a nickel (Ni)-decorated carboxylated polypyrrole nanoparticle (cPPyNP)-FET that offers the detection of liquid and gaseous cadaverine (CV). The TAAR13c, specifically binding to CV, which is an indicator of food spoilage, was successfully constructed in NDs. The NBN was fabricated by the oriented assembly of TAAR13c-embedded NDs (T13NDs) onto the transistor with Ni/cPPyNPs. The NBN showed high performance in selectivity and sensitivity for the detection of CV, with excellent stability in both aqueous and gas phases. Moreover, the NBN allowed efficient measurement of corrupted real-food samples. It demonstrates the ND-based device can allow the practical biosensor that provides high stability in the gas phase. English AMER CHEMICAL SOC FIELD-EFFECT TRANSISTOR LARGE-SCALE PRODUCTION OLFACTORY RECEPTOR ESCHERICHIA-COLI AMINE SENSOR EXPRESSION NANOPARTICLES TRANSDUCERS MIMICKING NANOTUBES Ultrasensitive, Selective, and Highly Stable Bioelectronic Nose That Detects the Liquid and Gaseous Cadaverine Article 10.1021/acs.analchem.9b01068 1 ANALYTICAL CHEMISTRY, v.91, no.19, pp.12181 - 12190 ANALYTICAL CHEMISTRY 91 19 12181 12190 scie scopus 000488993000011 2-s2.0-85072791403 Chemistry, Analytical Chemistry Article FIELD-EFFECT TRANSISTOR LARGE-SCALE PRODUCTION OLFACTORY RECEPTOR ESCHERICHIA-COLI AMINE SENSOR EXPRESSION NANOPARTICLES TRANSDUCERS MIMICKING NANOTUBES