Kim, Moon-Ju Yun, Tae Gyeong Noh, Joo-Yoon Park, Jong-Min Kang, Min-Jung Pyun, Jae-Chul 2024-01-19T20:00:42Z 2024-01-19T20:00:42Z 2021-09-02 2019-06-05 1944-8244 https://pubs.kist.re.kr/handle/201004/119889 A combination nanostructured matrix with metal Au nanoislands and semiconductor TiO2 nanowires is presented to enhance both desorption and ionization efficiency in laser desorption/ionization (LDI) mass spectrometry. The heterostructure of Au nanoislands on TiO2 nanowires was fabricated via (1) TiO2 nanowire synthesis through a modified wet-corrosion method and (2) Au nanoisland formation through thermal annealing of a sputtered Au layer on the TiO2 nanowires. Herein, the synergistic effect of this heterostructure for highly efficient ion production was experimentally elucidated in terms of the formation of high temperature on the surface of Au and the creation of a Schottky barrier at the Au-TiO2 interface. Finally, four types of immunosuppressors were analyzed to demonstrate the improved ionization performance of the heterostructure for LDI mass spectrometry. English American Chemical Society SURFACE-PLASMON RESONANCE HYDROTHERMAL TREATMENT DESORPTION-IONIZATION GOLD NANOPARTICLES RECENT PROGRESS MATRIX CHIP NANOMATERIALS FABRICATION MOLECULES Synergistic Effect of the Heterostructure of Au Nanoislands on TiO2 Nanowires for Efficient Ionization in Laser Desorption/Ionization Mass Spectrometry Article 10.1021/acsami.9b03386 1 ACS Applied Materials & Interfaces, v.11, no.22, pp.20509 - 20520 ACS Applied Materials & Interfaces 11 22 20509 20520 scie scopus 000470938500093 2-s2.0-85066398773 Nanoscience & Nanotechnology Materials Science, Multidisciplinary Science & Technology - Other Topics Materials Science Article SURFACE-PLASMON RESONANCE HYDROTHERMAL TREATMENT DESORPTION-IONIZATION GOLD NANOPARTICLES RECENT PROGRESS MATRIX CHIP NANOMATERIALS FABRICATION MOLECULES Au-TiO2 heterostructure wet corrosion LDI mass spectrometry thermal desorption differential scanning calorimetry (DSC) photocatalytic ionization Schottky heterojunction synergistic effect