Nanda, Sitansu Sekhar Hembram, K. P. S. S. Lee, Jae-Kap Kim, Kwangmeyung Selvan, Subramanian Tamil Yi, Dong Kee 2024-01-19T20:01:59Z 2024-01-19T20:01:59Z 2021-09-02 2019-06 2574-0970 https://pubs.kist.re.kr/handle/201004/119955 Anisotropic metal nanostructures (e.g., Au Ag, Au Cu) are emerging for biomedical and catalytic applications in recent years. Herein, we report a modified synthesis of Cu Au tripod nanocrystals through the controlled nucleation and growth process with judicious purification for photothermal based anticancer therapy. The distribution of nanocrystals in tripod was analyzed by STEM-EDX mapping, indicating the formation of Cu Au alloy nanocrystals. Theoretical calculations showed the possible formation of alloy structures, that is, Cu3Au, Cu Au, and CuAu3 and confirmed that their stability in the following order: CuAu3 < Cu Au < Cu3Au. These stable tripods exhibited a well pronounced photothermal effect as demonstrated by experimental and simulation photothermal studies. Cancer cells treated with nanocrystals upon NIR laser exposure showed promising therapeutic effects. English AMER CHEMICAL SOC CORE-SHELL NANOCUBES GOLD NANORODS ANTIBACTERIAL ACTIVITY METAL NANOPARTICLES OPTICAL-PROPERTIES NANOCRYSTALS COPPER SHAPE NANOMATERIALS GROWTH Experimental and Theoretical Structural Characterization of Cu-Au Tripods for Photothermal Anticancer Therapy Article 10.1021/acsanm.9b00634 1 ACS APPLIED NANO MATERIALS, v.2, no.6, pp.3735 - 3742 ACS APPLIED NANO MATERIALS 2 6 3735 3742 scopus 000473827600046 2-s2.0-85068603834 Nanoscience & Nanotechnology Materials Science, Multidisciplinary Science & Technology - Other Topics Materials Science Article CORE-SHELL NANOCUBES GOLD NANORODS ANTIBACTERIAL ACTIVITY METAL NANOPARTICLES OPTICAL-PROPERTIES NANOCRYSTALS COPPER SHAPE NANOMATERIALS GROWTH Cu-Au tripods bimetallic nanocrystals cancer cells photothermal therapy NIR laser