Qian, Linghui Pan, Sijun Lee, Jun-Seok Ge, Jingyan Li, Lin Yao, Shao Q. 2024-01-19T21:01:51Z 2024-01-19T21:01:51Z 2021-09-02 2019-01-25 1359-7345 https://pubs.kist.re.kr/handle/201004/120450 c-Jun N-terminal kinases (JNKs) are involved in critical cellular functions. Herein, small-molecule JNK-targeting probes are reported based on a covalent inhibitor. Together with newly developed two-photon fluorescence Turn-ON reporters and chemoproteomic studies, we showed that some probes may be suitable for live-cell imaging and profiling of JNKs. English ROYAL SOC CHEMISTRY PHOTO-CROSS-LINKERS DISCOVERY JNK STRATEGIES CHEMISTRY DYNAMICS DESIGN Live-cell imaging and profiling of c-Jun N-terminal kinases using covalent inhibitor-derived probes Article 10.1039/c8cc09558b 1 CHEMICAL COMMUNICATIONS, v.55, no.8, pp.1092 - 1095 CHEMICAL COMMUNICATIONS 55 8 1092 1095 scie scopus 000458544800016 2-s2.0-85060237671 Chemistry, Multidisciplinary Chemistry Article PHOTO-CROSS-LINKERS DISCOVERY JNK STRATEGIES CHEMISTRY DYNAMICS DESIGN c-Jun N-terminal kinase inhibitor