Han, Cheol-Min Lih, Eugene Choi, Seul-Ki Bedair, Tarek M. Lee, Young-Jae Park, Wooram Han, Dong Keun Son, Jun Sik Joung, Yoon Ki 2024-01-19T21:31:38Z 2024-01-19T21:31:38Z 2022-01-10 2018-11 1226-086X https://pubs.kist.re.kr/handle/201004/120720 In this study, a polydioxanone (PDO) and poly(L-lactic acid) (PLLA) sheath-core biphasic monofilament was designed to develop an esophageal stent with improved mechanical properties and controlled biodegradability. The radial force of PDO/PLLA sheath-core stent was 10.24 N, while that of PDO stent was 5.64 N. Deteriorations of tensile strength, elastic modulus and elongation during degradation test were also delayed on PDO/PLLA group. Hyaluronic acid-dopamine conjugate and BaSO4/PDO conjugate coating layers provided improved tissue adhesion strength and reasonable X-ray contrast, respectively. Taken all together, the sheath-core filaments with tissue adhesive and radiopaque properties will be useful in designing esophageal stents. (C) 2018 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved. English 한국공업화학회 Biodegradable sheath-core biphasic monofilament braided stent for bio-functional treatment of esophageal strictures Article 10.1016/j.jiec.2018.07.014 1 Journal of Industrial and Engineering Chemistry, v.67, pp.396 - 406 Journal of Industrial and Engineering Chemistry 67 396 406 N scie scopus kci ART002405713 000448095700040 2-s2.0-85050402348 Chemistry, Multidisciplinary Engineering, Chemical Chemistry Engineering Article HYALURONIC-ACID MECHANICAL-PROPERTIES SILICONE-RUBBER CROSS-LINKING BENIGN ADHESIVE DELIVERY DEGRADATION SCAFFOLDS HYDROGELS Esophageal stent Polydioxanone Poly(L-lactic acid) Sheath-core monofilament Surface treatments