Kim, Young-Kwan Landis, Ryan Vachet, Richard W. Rotello, Vincent M. 2024-01-19T21:32:33Z 2024-01-19T21:32:33Z 2021-09-05 2018-10-24 1944-8244 https://pubs.kist.re.kr/handle/201004/120771 Self-oxidative copolymerization of dopamine with alpha-cyano-4-hydroxycinnamic acid (CHCA) provides an efficient and multifunctional platform for laser desorption/ionization time-of-flight mass spectrometry (LDI-TOF-MS) analysis. The polydopamine coating layer embedded with the CHCA matrix can be readily formed on nanomaterials and solid substrates without additional surface treatments to generate an efficient LDI-TOF-MS platform for the analysis of small molecules as well as synthetic polymers. This coating can be further functionalized with specific ligands for target enrichment from complex biological media, providing analyte capture for subsequent LDI-TOF-MS analysis. English American Chemical Society GRAPHENE OXIDE DESORPTION/IONIZATION NANOPARTICLES DESORPTION ACID Matrix-Incorporated Polydopamine Layer as a Simple, Efficient, and Universal Coating for Laser Desorption/lonization Time-of-Flight Mass Spectrometric Analysis Article 10.1021/acsami.8b10990 1 ACS Applied Materials & Interfaces, v.10, no.42, pp.36361 - 36368 ACS Applied Materials & Interfaces 10 42 36361 36368 scie scopus 000448754500076 2-s2.0-85054959008 Nanoscience & Nanotechnology Materials Science, Multidisciplinary Science & Technology - Other Topics Materials Science Article GRAPHENE OXIDE DESORPTION/IONIZATION NANOPARTICLES DESORPTION ACID coating hybrid dopamine matrix enrichment mass spectrometry