Yim, Sehyuk Oh, Ye-Eun Jeong, Jinwoo Ihn, Yong Seok Hwang, Donghyun Oh, Sang-Rok Kim, Keehoon 2024-01-19T21:33:52Z 2024-01-19T21:33:52Z 2021-09-05 2018-10 1083-4435 https://pubs.kist.re.kr/handle/201004/120842 This paper introduces a new type of miniature device to insert an intrafascicular electrode into a peripheral nervous system that is covered with tough tissue membranes. The developed device is called nerve electrode insertion tool (NEIT) and consists of a nerve holder unit and an electrode insertion unit. Users can easily adjust the insertion position and direction of nerve electrodes while freely manipulating this compact handheld device. This paper introduces the form, configuration, and underlying mechanisms of the device and related surgical procedure. Utility tests using elastomer-made nerve models show that the electrode insertion time and position accuracy, respectively, improve from 72.1 to 4.17 s and 0.37 to 0.11 mm when employing the NEIT. Animal experiment results show that multishank planar electrodes (2 x 2 mm(2)) are successfully implanted into sciatic nerves of six rats. Treadmill tests and histological analysis present the neural functions of all the treated nerves are successfully recovered after three weeks. We expect the NEIT to be employed for other kinds of nerve electrodes and simplify the surgical process in neural engineering research. English IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC SCIATIC-NERVE STIMULATION ARRAY DESIGN TIME Handheld Nerve Electrode Insertion Tool Article 10.1109/TMECH.2018.2864978 1 IEEE-ASME TRANSACTIONS ON MECHATRONICS, v.23, no.5, pp.2525 - 2530 IEEE-ASME TRANSACTIONS ON MECHATRONICS 23 5 2525 2530 scie scopus 000447942600047 2-s2.0-85052602140 Automation & Control Systems Engineering, Manufacturing Engineering, Electrical & Electronic Engineering, Mechanical Automation & Control Systems Engineering Article SCIATIC-NERVE STIMULATION ARRAY DESIGN TIME Biomedical electrodes micro electrodes neural engineering surgical instruments