Moon, Hyunyoung Yoon, Hojong Lim, Changjin Jang, Jaebong Yi, Jong-Jae Lee, Jae Kyun Lee, Jeeyeon Na, Younghwa Son, Woo Sung Kim, Seok-Ho Suh, Young-Ger 2024-01-19T22:01:58Z 2024-01-19T22:01:58Z 2021-09-03 2018-09 1420-3049 https://pubs.kist.re.kr/handle/201004/120992 The versatile synthesis of (-)-6-desmethyl-fluvirucinine A(1) was accomplished at a 24% overall yield through a thirteen-step process from a known vinylpiperidine. The key part involved the elaboration of the distal stereocenters and a macrolactam skeleton via conformationally-induced diastereocontrol and the iterative aza-Claisen rearrangements of lactam precursors. English MDPI INFLUENZA-A VIRUS ENANTIOSELECTIVE TOTAL-SYNTHESIS AZA-CLAISEN REARRANGEMENT N,O-ACETAL TMS ETHER ANTHELMINTIC MACROLACTAMS VERSATILE CONVERSION SCH 38516 FLUVIRUCIN-B2 ALKALOIDS AGLYCON Asymmetric Synthesis of (-)-6-Desmethyl-Fluvirucinine A(1) via Conformationally-Controlled Diastereoselective Lactam-Ring Expansions Article 10.3390/molecules23092351 1 MOLECULES, v.23, no.9 MOLECULES 23 9 scie scopus 000447365100262 2-s2.0-85053621093 Biochemistry & Molecular Biology Chemistry, Multidisciplinary Biochemistry & Molecular Biology Chemistry Article INFLUENZA-A VIRUS ENANTIOSELECTIVE TOTAL-SYNTHESIS AZA-CLAISEN REARRANGEMENT N,O-ACETAL TMS ETHER ANTHELMINTIC MACROLACTAMS VERSATILE CONVERSION SCH 38516 FLUVIRUCIN-B2 ALKALOIDS AGLYCON fluvirucinine aza-Claisen rearrangement amidoalkylation