Kang, Seounghun Shin, Woojun Kang, Kyunglee Choi, Myung-Ho Kim, Young-Jin Kim, Young-Kwan Min, Dal-Hee Jang, Hongje 2024-01-19T23:01:24Z 2024-01-19T23:01:24Z 2021-09-03 2018-04-25 1944-8244 https://pubs.kist.re.kr/handle/201004/121459 Gold nanomaterials are commonly used in biomedical applications owing to their excellent biocompatibility and unique physicochemical and optical properties, whereas Pd nanomaterials are mainly used as catalysts. Here, we re-examined the possible applications of Pd nanomaterials. Reducing agent-assisted excessive galvanic replacement-mediated porous Au nanoplates, porous Pt nanoplates, and porous Pd nanoplate synthesis enabled us to compare the properties and efficiency of nanoplates composed of three metal elements (Au, Pt, and Pd). According to our analytical results, porous Pd nanoplates exhibited exceptional all-round excellence in photothermal conversion, therapeutic gene loading/releasing, cytotoxicity, and in vitro combination cancer treatment. We believe that this discovery broadens the potential applications of metal nanomaterials, with an emphasis on more efficient biomedical applications in limited conventional fields. English American Chemical Society GALVANIC REPLACEMENT GOLD NANOPARTICLES DRUG-DELIVERY PLATINUM NANOPARTICLES POLYMERIC NANOPARTICLES HOLLOW NANOSTRUCTURES FACILE SYNTHESIS SIZE CONJUGATION AGGREGATION Revisiting of Pd Nanoparticles in Cancer Treatment: All-Round Excellence of Porous Pd Nanoplates in Gene-Thermo Combinational Therapy Article 10.1021/acsami.8b01000 1 ACS Applied Materials & Interfaces, v.10, no.16, pp.13819 - 13828 ACS Applied Materials & Interfaces 10 16 13819 13828 scie scopus 000431150900063 2-s2.0-85045946076 Nanoscience & Nanotechnology Materials Science, Multidisciplinary Science & Technology - Other Topics Materials Science Article GALVANIC REPLACEMENT GOLD NANOPARTICLES DRUG-DELIVERY PLATINUM NANOPARTICLES POLYMERIC NANOPARTICLES HOLLOW NANOSTRUCTURES FACILE SYNTHESIS SIZE CONJUGATION AGGREGATION cancer therapy drug delivery galvanic replacement noble metal photothermal conversion