Jun, Indong Han, Hyung-Seop Edwards, James R. Jeon, Hojeong 2024-01-19T23:05:00Z 2024-01-19T23:05:00Z 2021-09-03 2018-03 1661-6596 https://pubs.kist.re.kr/handle/201004/121652 Electrospinning has been used for the fabrication of extracellular matrix (ECM)-mimicking fibrous scaffolds for several decades. Electrospun fibrous scaffolds provide nanoscale/microscale fibrous structures with interconnecting pores, resembling natural ECM in tissues, and showing a high potential to facilitate the formation of artificial functional tissues. In this review, we summarize the fundamental principles of electrospinning processes for generating complex fibrous scaffold geometries that are similar in structural complexity to the ECM of living tissues. Moreover, several approaches for the formation of three-dimensional fibrous scaffolds arranged in hierarchical structures for tissue engineering are also presented. English Multidisciplinary Digital Publishing Institute (MDPI) Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication Article 10.3390/ijms19030745 1 International Journal of Molecular Sciences, v.19, no.3 International Journal of Molecular Sciences 19 3 Y scie scopus 000428309800102 2-s2.0-85043484260 Biochemistry & Molecular Biology Chemistry, Multidisciplinary Biochemistry & Molecular Biology Chemistry Review FEMTOSECOND LASER-ABLATION EXTRACELLULAR-MATRIX COMPOSITE SCAFFOLDS BONE REGENERATION CELL-MIGRATION NANOFIBERS FIBERS GELATIN TENDON ORGANIZATION electrospinning nanofiber scaffolds tissue engineering extracellular matrix-mimicking geometries