Lee, Jeeyeon Park, Ho Yong Kim, Wan Wook Jeong, Ji Yun Lee, Yong-Deok Choi, Mi-Hwa Kim, Sehoon Park, Ji-Young Jung, Jin Hyang 2024-01-20T00:33:57Z 2024-01-20T00:33:57Z 2021-09-05 2017-09 1549-5418 https://pubs.kist.re.kr/handle/201004/122346 Purpose: Minimally invasive treatments for early breast cancer have been reported. The objective of this study was to evaluate and compare two such treatments, laser ablation and photodynamic therapy (PDT), regarding their therapeutic efficacy for breast cancer. Methods: Breast tumors were induced in 12 mice models. The treatment options were classified into four groups: control group (without any treatment, A), group treated only with laser ablation (B), group treated only with PDT (C), and group treated with the combination of laser ablation followed by PDT (D). The treatment effects were compared among these groups. Results: Among the groups, the group D underwent the most effective treatment for breast cancer. Not only were the breast cancer cells necrotized by laser ablation, but the tumor margin was also managed by PDT. Conclusions: The treatment method combining laser ablation and PDT showed superior results to single treatment techniques using just one of these approaches. English MARY ANN LIEBERT, INC BASAL-CELL CARCINOMA RADIOFREQUENCY ABLATION RADIATION-THERAPY MARGIN ASSESSMENT METHYLENE-BLUE FIRING FIBER TUMOR CRYOTHERAPY LUMPECTOMY PHOTOFRIN Combination Treatment with Photodynamic Therapy and Laser Ablation in Breast Cancer: An Animal Model Study Article 10.1089/pho.2017.4291 1 PHOTOMEDICINE AND LASER SURGERY, v.35, no.9, pp.505 - 512 PHOTOMEDICINE AND LASER SURGERY 35 9 505 512 scie scopus 000410391300009 2-s2.0-85029228137 Surgery Surgery Article BASAL-CELL CARCINOMA RADIOFREQUENCY ABLATION RADIATION-THERAPY MARGIN ASSESSMENT METHYLENE-BLUE FIRING FIBER TUMOR CRYOTHERAPY LUMPECTOMY PHOTOFRIN breast carcinoma photodynamic therapy laser ablation