Choi, Sun Birarda, Giovanni 2024-01-20T01:00:57Z 2024-01-20T01:00:57Z 2021-09-05 2017-08-03 1520-6106 https://pubs.kist.re.kr/handle/201004/122432 During natural drying process, all solutions and suspensions tend to form the so-called "coffee-ring" deposits. This phenomenon, by far, has been interpreted by the hydrodynamics of evaporating fluids. However, in this study, by applying Fourier transform infrared imaging (FTIRI), it is possible to observe the segregation and separation of a protein mixture at the "ring", hence we suggest a new way to interpret "coffee-ring effect" of solutions. The results explore the dynamic process that leads to the ring formation in case of model plasma proteins, such as BGG (bovine ? globulin), BSA (bovine serum albumin), and Hfib (human fibrinogen), and also report fascinating discovery of the segregation at the ring deposits of two model proteins BGG and BSA, which can be explained by an energy kinetic model, only. The investigation suggests that the coffee-ring effect of solute in an evaporating solution drop is driven by an energy gradient created from change of particle-water-air interfacial energy configuration. English AMER CHEMICAL SOC INFRARED-SPECTROSCOPY PATTERN-FORMATION EVAPORATION DEPOSITION STAINS SUPPRESSION ADSORPTION CONVECTION TRANSPORT REVERSES Protein Mixture Segregation at Coffee-Ring: Real-Time Imaging of Protein Ring Precipitation by FTIR Spectromicroscopy Article 10.1021/acs.jpcb.7b05131 1 JOURNAL OF PHYSICAL CHEMISTRY B, v.121, no.30, pp.7359 - 7365 JOURNAL OF PHYSICAL CHEMISTRY B 121 30 7359 7365 scie scopus 000407189200015 2-s2.0-85026908247 Chemistry, Physical Chemistry Article INFRARED-SPECTROSCOPY PATTERN-FORMATION EVAPORATION DEPOSITION STAINS SUPPRESSION ADSORPTION CONVECTION TRANSPORT REVERSES