Kang, Tae Hoon Lee, Yun Me Lee, Won Jung Hwang, Eui Il Park, Ki Duk Choi, Gyung Ja Moon, Jae Sun Park, Ho-Yong Kim, Sung Uk 2024-01-20T01:03:41Z 2024-01-20T01:03:41Z 2021-09-05 2017-07 1017-7825 https://pubs.kist.re.kr/handle/201004/122581 Two dimeric sesquiterpenes were separated from Chloranthus japonicus Sieb. and identified as shizukaols C and F. They exhibited potent antifungal activities (MICs = 4-16 mu g/ml) in vitro against various plant pathogenic fungi (Pythium ultimum, Phytophthora infestans, Botrytis cinerea, Colletotrichum lagenarium, Alternaria kikuchiana, and Magnaporthe grisea). Shizukaol C showed 88% and 91% protective activities in the greenhouse against Puccinia recondita (wheat leaf rust) and Phytophthora infestans (tomato late blight), respectively, at 100 mu g/ml; shizukaol F exhibited 93% antifungal activity against Puccinia recondita at the same concentration. Therefore, these compounds might serve as interesting candidates for effective antifungal agents. English KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY CHEMICAL-CONSTITUENTS PLANTS HENRYI SUPPRESSION Antifungal Activities of Dimeric Sesquiterpenes, Shizukaols C and F, Isolated from Chloranthus japonicus Sieb. Article 10.4014/jmb.1612.12051 1 JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.27, no.7, pp.1272 - 1275 JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 27 7 1272 1275 scie scopus kci ART002246509 000408232100009 2-s2.0-85026489483 Biotechnology & Applied Microbiology Microbiology Biotechnology & Applied Microbiology Microbiology Article CHEMICAL-CONSTITUENTS PLANTS HENRYI SUPPRESSION Chloranthus japonicus Sieb. shizukaol C shizukaol F antifungal activity Phytophthora infestans Puccinia recondita