Kim, Taejung Jeong, Kyu Hyuk Kang, Ki Sung Nakata, Masaya Ham, Jungyeob 2024-01-20T01:34:25Z 2024-01-20T01:34:25Z 2021-09-01 2017-04-03 1434-193X https://pubs.kist.re.kr/handle/201004/122858 A simple method for the preparation of arylnaphthalene lactone natural products was developed and used to synthesize diphyllin (10), justicidin A (12), cilinaphthalide B (13), taiwanin E (15), chinensinaphthol (16), taiwanin E methyl ether (17), chinensinaphthol methyl ether (18), justicidin C (21), and justicidin D (22). Key steps of the syntheses include the Hauser-Kraus annulation of cyanophthalides 7a and 7b and Suzuki-Miyaura cross-coupling reactions between arylnaphthalene lactones that contain a sulfonate group (i.e., 9, 14, 19, and 20) and various potassium aryltrifluoroborates. English WILEY-V C H VERLAG GMBH CROSS-COUPLING REACTIONS JUSTICIA-PROCUMBENS 1-ARYLNAPHTHALENE LIGNAN PHYLLANTHUS-MYRTIFOLIUS BIOLOGICAL EVALUATION DERIVATIVES ANALOGS BIOEVALUATION NEOLIGNANS INHIBITORS An Optimized and General Synthetic Strategy To Prepare Arylnaphthalene Lactone Natural Products from Cyanophthalides Article 10.1002/ejoc.201601611 1 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, v.2017, no.13, pp.1704 - 1712 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2017 13 1704 1712 scie scopus 000398575300003 2-s2.0-85017154457 Chemistry, Organic Chemistry Article CROSS-COUPLING REACTIONS JUSTICIA-PROCUMBENS 1-ARYLNAPHTHALENE LIGNAN PHYLLANTHUS-MYRTIFOLIUS BIOLOGICAL EVALUATION DERIVATIVES ANALOGS BIOEVALUATION NEOLIGNANS INHIBITORS Total synthesis Natural products Annulation Cross-coupling Lactones