Suh, Young-Ger Lim, Changjin Sim, Jaehoon Lee, Jae Kyun Surh, Young-Joon Paek, Seung-Mann 2024-01-20T02:03:53Z 2024-01-20T02:03:53Z 2021-09-01 2017-02-03 0022-3263 https://pubs.kist.re.kr/handle/201004/123076 A divergent synthetic methodology for a tabernaemontanine-related alkaloid was developed. The synthetic route features practical improvements in the Pictet-Spengler cyclization for the tetrahydro-fi-carboline intermediate and an unprecedented tandem Reformatsky aza-Claisen rearrangement to create the core carbon skeleton and stereochemistries of tabernaemontanine-related alkaloids. English AMER CHEMICAL SOC ENANTIOSPECIFIC TOTAL-SYNTHESIS INDOLE ALKALOIDS BISINDOLE ALKALOIDS TABEMAEMONTANA VOBASINE Construction of the Azacyclic Core of Tabernaemontanine-Related Alkaloids via Tandem Reformatsky Aza-Claisen Rearrangement Article 10.1021/acs.joc.6b02648 1 JOURNAL OF ORGANIC CHEMISTRY, v.82, no.3, pp.1464 - 1470 JOURNAL OF ORGANIC CHEMISTRY 82 3 1464 1470 scie scopus 000394472900018 2-s2.0-85011319815 Chemistry, Organic Chemistry Article ENANTIOSPECIFIC TOTAL-SYNTHESIS INDOLE ALKALOIDS BISINDOLE ALKALOIDS TABEMAEMONTANA VOBASINE Pictet-Spengler cyclization carbon skeleton and stereochemistries X-ray crystallographic structure