Garg, PanKaj Pandey, Shambhavi Kim, Hong-Nam Seonwoo, Hoon Park, Sunho Choi, Kyoung Soon Jang, Kyoung-Je Hyun, Hoon Choung, Phil-Hoon Kim, Jangho Chung, Jong Hoon 2024-01-20T03:03:13Z 2024-01-20T03:03:13Z 2021-09-03 2016-11 2046-2069 https://pubs.kist.re.kr/handle/201004/123536 Here, we report the synergistic effects of hyperosmotic and nanotopographical cues designed using non-viral vectors and nanopatterned matrices for gene delivery. We show that efficiency of gene delivery can be further enhanced by two factors in combination, indicating the importance of synergistic cues in designing non-viral gene delivery platforms and strategies for gene therapy. English ROYAL SOC CHEMISTRY MESENCHYMAL STEM-CELLS ENDOCYTOSIS DIFFERENTIATION TRANSFECTION STIFFNESS SYSTEMS MATRIX SIRNA Synergistic effects of hyperosmotic polymannitol based non-viral vectors and nanotopographical cues for enhanced gene delivery Article 10.1039/c6ra09348e 1 RSC ADVANCES, v.6, no.112, pp.111233 - 111238 RSC ADVANCES 6 112 111233 111238 scie scopus 000389463600084 2-s2.0-84997765911 Chemistry, Multidisciplinary Chemistry Article MESENCHYMAL STEM-CELLS ENDOCYTOSIS DIFFERENTIATION TRANSFECTION STIFFNESS SYSTEMS MATRIX SIRNA