Lee, Sang-Hyun Yun, Eun Ju Kim, Jungyeon Lee, Sang Jun Um, Youngsoon Kim, Kyoung Heon 2024-01-20T03:30:35Z 2024-01-20T03:30:35Z 2021-09-05 2016-10 0175-7598 https://pubs.kist.re.kr/handle/201004/123631 Butanol is considered an attractive biofuel and a commercially important bulk chemical. However, economical production of butanol by solventogenic clostridia, e.g., via fermentative production of acetone-butanol-ethanol (ABE), is hampered by low fermentation performance, mainly as a result of toxicity of butanol to microorganisms and high substrate costs. Recently, sugars from marine macroalgae and syngas were recognized as potent carbon sources in biomass feedstocks that are abundant and do not compete for arable land with edible crops. With the aid of systems metabolic engineering, many researchers have developed clostridial strains with improved performance on fermentation of these substrates. Alternatively, fermentation strategies integrated with butanol recovery processes such as adsorption, gas stripping, liquid-liquid extraction, and pervaporation have been designed to increase the overall titer of butanol and volumetric productivity. Nevertheless, for economically feasible production of butanol, innovative strategies based on recent research should be implemented. This review describes and discusses recent advances in the development of biomass feedstocks, microbial strains, and fermentation processes for butanol production. English Springer Verlag Biomass, strain engineering, and fermentation processes for butanol production by solventogenic clostridia Article 10.1007/s00253-016-7760-9 1 Applied Microbiology and Biotechnology, v.100, no.19, pp.8255 - 8271 Applied Microbiology and Biotechnology 100 19 8255 8271 N scie scopus 000383242500001 2-s2.0-84982153344 Biotechnology & Applied Microbiology Biotechnology & Applied Microbiology Review ACETOBUTYLICUM ATCC 824 TERM CONTINUOUS CULTIVATION FED-BATCH FERMENTATION SOLE CARBON SOURCE N-BUTANOL ETHANOL FERMENTATION TRANSCRIPTIONAL ANALYSIS BIOFUEL PRODUCTION BACILLUS-SUBTILIS ESCHERICHIA-COLI Butanol Solventogenic clostridia Metabolic engineering Fermentation Butanol recovery