Lee, Ikho Lee, Seung-Woo Lee, Ki-Young Park, Chanoh Kim, Donghoon Lee, Jeong-Soo Yi, Hyunjung Kim, Byungsub 2024-01-20T04:02:28Z 2024-01-20T04:02:28Z 2021-09-05 2016-06-01 1530-437X https://pubs.kist.re.kr/handle/201004/123977 This paper presents a portable low-cost biosensor platform for ion-sensitive field-effect transistor (ISFET) and enzyme-based sensors. To meet various demands of diagnosis, our portable platform is designed to perform cyclic voltammetry, amperometry, and linear sweep voltammetry for enzyme-based sensor and ISFET sensor. For compatibility with various sensors which require various electrical driving schemes, our system can be easily reconfigured by simple switches. In addition, with disposable printed-circuit-board packages, sensors can be easily replaced. Our platform was tested with various sensors in various measurement methods. In cyclic voltammetry test with a model analyte K3Fe(CN)(6), a graph provided by our system has 4.79% relative error at a current peak compared with the data acquired by a 18 times more expensive commercial system. In cyclic voltammetry and amperometry tests with the laccase enzyme-based sensors, our system achieved sensitivities of 341 and 500 mu A/mM/cm(2), respectively. By running a sensitive SiNW ISFET on our platform in linear sweep voltammetry, we could build a low-cost portable pH sensor system. English IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC CHIP A Reconfigurable and Portable Highly Sensitive Biosensor Platform for ISFET and Enzyme-Based Sensors Article 10.1109/JSEN.2016.2541698 1 IEEE SENSORS JOURNAL, v.16, no.11, pp.4443 - 4451 IEEE SENSORS JOURNAL 16 11 4443 4451 scie scopus 000375563700056 2-s2.0-84968877301 Engineering, Electrical & Electronic Instruments & Instrumentation Physics, Applied Engineering Instruments & Instrumentation Physics Article CHIP Biosensor platform SiNW ISFET enzyme-based catechol sensor amperometry cyclic voltammetry linear sweep voltammetry