Hong, Seong Cheol Murale, Dhiraj P. Lee, Jun-Seok 2024-01-20T04:30:16Z 2024-01-20T04:30:16Z 2022-01-10 2016-05 1386-2073 https://pubs.kist.re.kr/handle/201004/124100 Herein, we report the first 48-membered, dansyl-based, combinatorial fluorescent library. From the electronic and structural properties of the probes, we analyzed their optical properties and chemical yields, with an average of 49 %. The molecules were examined for their pH responses, and DS-2 and DS-45 showed blue-shifts, whereas DS-7 and DS-40 showed red-shifts in wavelength with increasing pH. Finally, cell permeability was investigated by treating SNU-2292 cells. Our results demonstrate the potential application of this library in biosensors, bio-imaging and pH indicators. English BENTHAM SCIENCE PUBL LTD LARGE STOKES SHIFT CHLORIDE DERIVATIZATION FLUORESCENCE PROPERTIES MASS-SPECTROMETRY ACID DYES HPLC Combinatorial Dansyl Library and its Applications to pH-Responsive Probes Article 10.2174/1386207319666160408150203 1 COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, v.19, no.5, pp.347 - 352 COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 19 5 347 352 scie scopus 000378054400002 2-s2.0-84974801163 Biochemical Research Methods Chemistry, Applied Pharmacology & Pharmacy Biochemistry & Molecular Biology Chemistry Pharmacology & Pharmacy Article LARGE STOKES SHIFT CHLORIDE DERIVATIZATION FLUORESCENCE PROPERTIES MASS-SPECTROMETRY ACID DYES HPLC Combinatorial chemistry dansyl chloride pH sensor