Kim, Young-Min Kim, Chang-Ho Park, Mi-Ran Song, Soo-Chang 2024-01-20T04:34:49Z 2024-01-20T04:34:49Z 2021-09-05 2016-03 0253-2964 https://pubs.kist.re.kr/handle/201004/124339 Hemostatic agents are important for minimizing blood loss to improve the patient status during surgery. Most currently used hemostatic agents have limitations such as poor adhesion in the presence of biological fluids, allergic response, and inflammation. We developed a dopamine-conjugated injectable thermosensitive hydrogel to overcome these limitations through the application of a relatively safe hydrogel for biocompatibility, thermosensitivity to induce tight interactions, and mussel-induced adhesion. Dopamine as a mussel inspired material was conjugated to an injectable thermosensitive poly(organophosphazene) hydrogel, which showed the potential for application as a hemostatic agent because of its high biocompatibility, injectability, slow mass loss, easy preparation, and hemostatic effect. English WILEY-V C H VERLAG GMBH TISSUE ADHESIVES SEALANTS SURGERY Development of an Injectable Dopamine-conjugated Poly(organophophazene) Hydrogel for Hemostasis Article 10.1002/bkcs.10686 1 BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.37, no.3, pp.372 - 377 BULLETIN OF THE KOREAN CHEMICAL SOCIETY 37 3 372 377 scie scopus kci ART002089411 000371907500019 2-s2.0-84969373499 Chemistry, Multidisciplinary Chemistry Article TISSUE ADHESIVES SEALANTS SURGERY Hemostasis Hemostatic agent Poly(orgranophosphazene) Thermosensitive hydrogel Dopamine