Kim, Jo-Il Park, Jong-Min Noh, Joo-Yoon Hwang, Seong-Ju Kang, Min-Jung Pyun, Jae-Chul 2024-01-20T05:04:30Z 2024-01-20T05:04:30Z 2021-09-03 2016-01 0045-6535 https://pubs.kist.re.kr/handle/201004/124565 In this work, the wet-corrosion process for the synthesis of titanium oxide (TiO2) nanowires in the anatase phase was optimized as the solid matrix in MALDI-TOF mass spectrometry, and the solid matrix of the TiO2 nanowires was applied to the detection of antibiotics in a daily milk sample. The influence of the alkali concentration and the heat treatment temperature on the crystal structure of the TiO2 nanowires was investigated. The ionization activity of the TiO2 nanowires was estimated for each synthetic condition using amino acids as model analytes with low molecular weights. For the detection of antibiotics in milk, benzylpenicillin was spiked in daily milk samples, and MALDI-TOF mass spectrometry with the TiO2 nanowires was demonstrated to detect the benzylpenicillin at the cut-off concentration of the EU directive. (C) 2015 Elsevier Ltd. All rights reserved. English PERGAMON-ELSEVIER SCIENCE LTD TITANIUM-DIOXIDE SMALL MOLECULES DESORPTION-IONIZATION QUANTITATIVE-ANALYSIS LASER-DESORPTION STEEL TARGETS NANOPARTICLES ANATASE RESIDUES GRAPHENE Analysis of benzylpenicillin in milk using MALDI-TOF mass spectrometry with top-down synthesized TiO2 nanowires as the solid matrix Article 10.1016/j.chemosphere.2015.04.002 1 CHEMOSPHERE, v.143, pp.64 - 70 CHEMOSPHERE 143 64 70 scie scopus 000366776000010 2-s2.0-84951570043 Environmental Sciences Environmental Sciences & Ecology Article TITANIUM-DIOXIDE SMALL MOLECULES DESORPTION-IONIZATION QUANTITATIVE-ANALYSIS LASER-DESORPTION STEEL TARGETS NANOPARTICLES ANATASE RESIDUES GRAPHENE Titanium oxide nanowires MALDI-TOF mass spectrometry Antibiotics Milk