Park, Jinsoo Hwang, Kyo Seon Cho, Sungbo 2024-01-20T06:02:51Z 2024-01-20T06:02:51Z 2021-09-05 2015-10 1533-4880 https://pubs.kist.re.kr/handle/201004/124965 A circular interdigitated electrode (IDE) array for label-free and real-time impedance monitoring of cell growth was fabricated and evaluated. Both the width and spacing of fingers were 50 pm, and the exposed sensing area of the circular IDE was 1.3 similar to 3.4 mm. The electrical characteristics of the fabricated circular IDE were modeled as an equivalent circuit, and the values of the circuit parameters extrapolated from the fitting to the measured spectra in different concentrations of NaCl or sensing areas of the circular IDE were analyzed. During cell growth, the resistance of cells extrapolated from the fitting was increased and the maximum rate of change in the real part of the impedance was observed at frequencies of 10 to 22 kHz. The normalized real part of the impedance measured at 10 kHz during cell growth was increased more with decreasing the electrode sensing area, albeit the number of cells to be investigated showed a corresponding increase. English AMER SCIENTIFIC PUBLISHERS ARRAY SPECTROSCOPY BIOSENSORS ADHESION Dependence of Impedance Measurement Sensitivity of Cell Growth on Sensing Area of Circular Interdigitated Electrode Article 10.1166/jnn.2015.11230 1 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.15, no.10, pp.7886 - 7890 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 15 10 7886 7890 scie scopus 000365554600090 2-s2.0-84947233192 Chemistry, Multidisciplinary Nanoscience & Nanotechnology Materials Science, Multidisciplinary Physics, Applied Physics, Condensed Matter Chemistry Science & Technology - Other Topics Materials Science Physics Article ARRAY SPECTROSCOPY BIOSENSORS ADHESION Equivalent Circuit Electrochemical Impedance Spectroscopy Cellular Biosensor Label-Free Detection