Jeong, Keun-Seung Kim, Ho-Joong Lim, Hwa-Lim Ryu, Geun-Chang Seo, Eun-Sun You, Nam-Ho Jun, Jin 2024-01-20T07:02:12Z 2024-01-20T07:02:12Z 2021-09-04 2015-06 0253-2964 https://pubs.kist.re.kr/handle/201004/125414 A novel methacrylated polydimethylsiloxane (mPDMS) was synthesized for the preparation of silicone hydrogel (SiHy). The SiHy was functionalized with polysaccharides such as hyaluronic acid and alginic acid by construction of an interpenetrating polymer network (IPN) structure composed of cross-linked SiHy backbones and polysaccharide networks. We investigated the protein adsorption resistance, toxicity, wettability, optical transparency, and surface property of the SiHy. The synthesized SiHy exhibited the transmittance of over 90% and the improved surface hydrophilicity. Importantly, the amount of protein adsorbed on the polysaccharide-functionalized SiHy decreased significantly compared with unmodified SiHy. These results suggest that polysaccharide-modified SiHy may offer potential for ophthalmic materials as well as antibiofouling coating materials. English WILEY-V C H VERLAG GMBH PROTEIN ADSORPTION POLY(ETHYLENE GLYCOL) PHOSPHOLIPID POLYMER RESISTANCE Synthesis and Biocompatibility of Silicone Hydrogel Functionalized with Polysaccharide Article 10.1002/bkcs.10315 1 BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.36, no.6, pp.1649 - 1653 BULLETIN OF THE KOREAN CHEMICAL SOCIETY 36 6 1649 1653 scie scopus kci 000355986100016 2-s2.0-84936742235 Chemistry, Multidisciplinary Chemistry Article PROTEIN ADSORPTION POLY(ETHYLENE GLYCOL) PHOSPHOLIPID POLYMER RESISTANCE Silicone hydrogel Polysaccharide Protein adsorption Hyaluronic acid Contact lens