Lee, Juseok Jeon, Hojeong Haidar, Ayman Abdul-Khaliq, Hashim Veith, Michael Aktas, Cenk Kim, Youngjun 2024-01-20T07:32:55Z 2024-01-20T07:32:55Z 2021-09-05 2015-03 2314-6133 https://pubs.kist.re.kr/handle/201004/125698 A novel synthesis of a nanostructured cell adhesive surface is investigated for future stent developments. One-dimensional (1D) Al2O3 nanostructures were prepared by chemical vapor deposition of a single source precursor. Afterwards, recombinant filamentous bacteriophages which display a short binding motif with a cell adhesive peptide (RGD) on p3 and p8 proteins were immobilized on these 1D Al2O3 nanostructures by a simple dip-coating process to study the cellular response of human endothelial EA hy.926. While the cell density decreased on as-deposited 1D Al2O3 nanostructures, we observed enhanced cell proliferation and cell-cell interaction on recombinant phage overcoated 1D Al2O3 nanostructures. The recombinant phage overcoating also supports an isotropic cell spreading rather than elongated cell morphology as we observed on as-deposited Al2O3 1D nanostructures. English Hindawi Publishing Corporation Recombinant Phage Coated 1D Al2O3 Nanostructures for Controlling the Adhesion and Proliferation of Endothelial Cells Article 10.1155/2015/909807 1 BioMed Research International, v.2015 BioMed Research International 2015 N scie scopus 000355519800001 2-s2.0-84930965927 Biotechnology & Applied Microbiology Medicine, Research & Experimental Biotechnology & Applied Microbiology Research & Experimental Medicine Article recombinant phage nanostructure cell adhesion cell proliferation endothelial cell