Castro, Eric R. Manz, Andreas 2024-01-20T07:34:40Z 2024-01-20T07:34:40Z 2022-01-25 2015-02 0021-9673 https://pubs.kist.re.kr/handle/201004/125786 Microchip electrophoresis (MCE) was one of the earliest applications of the micro-total analysis system (mu-TAS) concept, whose aim is to reduce analysis time and reagent and sample consumption while increasing throughput and portability by miniaturizing analytical laboratory procedures onto a microfluidic chip. More than two decades on, electrophoresis remains the most common separation technique used in microfluidic applications. MCE-based instruments have had some commercial success and have found application in many disciplines. This review will consider the present state of MCE including recent advances in technology and both novel and routine applications in the laboratory. We will also attempt to assess the impact of MCE in the scientific community and its prospects for the future. (C) 2014 Elsevier B.V. All rights reserved. English ELSEVIER SCIENCE BV Present state of microchip electrophoresis: State of the art and routine applications Article 10.1016/j.chroma.2014.11.034 1 JOURNAL OF CHROMATOGRAPHY A, v.1382, pp.66 - 85 JOURNAL OF CHROMATOGRAPHY A 1382 66 85 N scie scopus 000349729600006 Biochemical Research Methods Chemistry, Analytical Biochemistry & Molecular Biology Chemistry Review ON-A-CHIP INTEGRATED CAPILLARY-ELECTROPHORESIS CONTACTLESS CONDUCTIVITY DETECTION NITRIC-OXIDE PRODUCTION MICROFLUIDIC-CHIP HIGH-THROUGHPUT LABEL-FREE AMPEROMETRIC DETECTION FLUORESCENCE DETECTION ZONE ELECTROPHORESIS Microfluidics Electrophoresis