Lee, K. -S. Han, H. -S. Kim, Y. -C. Lo Han, J. H. H-Seung, R. Lee, H. -S. Chang, J. -S. Lee, D. -H. 2024-01-20T08:00:38Z 2024-01-20T08:00:38Z 2021-09-04 2015-02 1432-8917 https://pubs.kist.re.kr/handle/201004/125829 The osteoconduction of porous bodies made of two kinds of calcium phosphate compounds was investigated by performing single level posterolateral spinal fusions on 20 New Zealand white rabbits. The animals were divided into two groups and implanted with bone graft substitute made of hydroxyapatite (HA) and beta-calcium pyrophosphate (beta-CPP) respectively. All animals were sacrificed after 12 weeks of surgery, and the fused bone masses were evaluated using manual palpation, uniaxial tensile strength measurement and histological evaluation. Fusion ratios and mean tensile strengths were similar for both beta-CPP and HA group. Light and scanning electron microscopy showed new bone growth into the pores, which was abundant in the both beta-CPP and HA group. However, the pore size of the beta-CPP implant was larger than that of HA, and faster bone growth was observed as beta-CPP was absorbed into the host's body. In conclusion, porous beta-CPP implants showed more desirable bone graft substitute characteristics due to their satisfactory osteoconductive ability and better biodegradation compared to porous HA implants. English MANEY PUBLISHING CERAMIC COMPOSITION PHOSPHATE CERAMICS IN-VITRO HYDROXYAPATITE BEHAVIOR INTERFACE INGROWTH Evaluation of porous beta-calcium pyrophosphate as bioresorbable bone graft substitute material Article 10.1179/1433075X14Y.0000000215 1 MATERIALS RESEARCH INNOVATIONS, v.19, no.2, pp.86 - 90 MATERIALS RESEARCH INNOVATIONS 19 2 86 90 scie scopus 000349114500002 2-s2.0-84920442237 Materials Science, Multidisciplinary Materials Science Article CERAMIC COMPOSITION PHOSPHATE CERAMICS IN-VITRO HYDROXYAPATITE BEHAVIOR INTERFACE INGROWTH Calcium phosphate Bone graft Bioresorption Osteoconduction