박성진 이이재 윤광석 강지윤 이수현 2024-01-20T08:02:15Z 2024-01-20T08:02:15Z 2021-09-06 2015-01 1225-5475 https://pubs.kist.re.kr/handle/201004/125908 This study demonstrates a polyimide nerve cuff electrode with a conductive polymer for improving recording signal quality at peripheral nerve. The nerve cuff electrodes with platinum (Pt), iridium oxide (IrOx), and poly(3,4-ethylenedioxythiophene): p-toluene sulfonate (PEDOT:pTS) were fabricated and investigated their electrical characteristics for improving recorded nerve signal quality. The fabricated nerve cuff electrodes with Pt, IrOx, and PEDOT:pTS were characterized their impedance and CDC by using electrochemical impedance spectroscopy (EIS) and cyclic voltammetry. The impedance of PEDOT:pTS measured at 1 kHz was 257Ω, which was extremely lower than the value of the nerve cuff electrodes with IrOx (15897Ω) and Pt (952Ω), respectively. Furthermore, the charge delivery capacity (CDC) of the nerve cuff electrode with PEDOT:pTS was dramatically increased to 62 times than the nerve cuff electrode with IrOx. In ex-vivo test using extracted sciatic nerve of spaque-dawley rat (SD rat), the PEDOT:pTS group exhibited higher signal-to-interference ratio than IrOx group. These results indicated that the nerve cuff electrode with PEDOT:pTS is promising for effective implantable nerve signal recording. Korean 한국센서학회 말초 신경 신호 기록의 효율성 개선을 위한 전도성 폴리머가 적용된 생체삽입형 커프형 신경전극 Implantable Nerve Cuff Electrode with Conductive Polymer for Improving Recording Signal Quality at Peripheral Nerve Article 10.5369/JSST.2015.24.1.22 2 센서학회지, v.24, no.1, pp.22 - 28 센서학회지 24 1 22 28 kci ART001958202 Nerve cuff electrode Neural signal recording Iridium oxide PEDOT:pTS ex-vivo test